ezh2 knockdown ezh2 shrnas Search Results


shrna plasmids for setd2 and ezh2 knockdown  (PSICOR Inc)
90
PSICOR Inc shrna plasmids for setd2 and ezh2 knockdown
Summary of identified human HMTs and their substrates.
Shrna Plasmids For Setd2 And Ezh2 Knockdown, supplied by PSICOR Inc, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/result/shrna plasmids for setd2 and ezh2 knockdown/product/PSICOR Inc
Average 90 stars, based on 1 article reviews
shrna plasmids for setd2 and ezh2 knockdown - by Bioz Stars, 2026-02
90/100 stars
  Buy from Supplier

Image Search Results


Summary of identified human HMTs and their substrates.

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: Summary of identified human HMTs and their substrates.

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques:

Frequency of HMT copy number alterations and mutations (%).

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: Frequency of HMT copy number alterations and mutations (%).

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques: Mutagenesis

Associations between CNA and expression, and comparison of mRNA expression between ccRCC and non-ccRCC kidney cancer subtypes.

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: Associations between CNA and expression, and comparison of mRNA expression between ccRCC and non-ccRCC kidney cancer subtypes.

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques: Expressing, Comparison

(A–F) Kaplan-Meier plots of overall survival associated with copy number and mRNA expression levels of three HMTs (NSD1, PRDM6, and EZH2) in renal cell carcinoma. (G) Multivariate analysis (Cox model, n=428) of genetic alteration and gene expression of 11 HMTs (ASH1L, PRDM8, SETD1A, PRDM9, PRDM6, EHMT1, NSD1, WHSC1L1, PRDM7, SUV420H1 and DOT1L) and their HR values, respectively.

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: (A–F) Kaplan-Meier plots of overall survival associated with copy number and mRNA expression levels of three HMTs (NSD1, PRDM6, and EZH2) in renal cell carcinoma. (G) Multivariate analysis (Cox model, n=428) of genetic alteration and gene expression of 11 HMTs (ASH1L, PRDM8, SETD1A, PRDM9, PRDM6, EHMT1, NSD1, WHSC1L1, PRDM7, SUV420H1 and DOT1L) and their HR values, respectively.

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques: Expressing, Gene Expression

(A-H) mRNA relative expression level of 8 HMTs (NSD1, PRDM6, EZH2, WHSC1L1, SETD2, ASH1L, SETD1A, and MECOM) in OSRC-2, ACHN, 786-O, and HK-2 cell lines, the lowest gene expression level was set as “1” among the four cell lines. Relative expression levels are shown as fold changes compared with “1”.

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: (A-H) mRNA relative expression level of 8 HMTs (NSD1, PRDM6, EZH2, WHSC1L1, SETD2, ASH1L, SETD1A, and MECOM) in OSRC-2, ACHN, 786-O, and HK-2 cell lines, the lowest gene expression level was set as “1” among the four cell lines. Relative expression levels are shown as fold changes compared with “1”.

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques: Expressing, Gene Expression

Integrative identification of critical HMTs in kidney cancer.

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: Integrative identification of critical HMTs in kidney cancer.

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques: Expressing

(A) qPCR analysis of relative expression of EZH2 in sh-LacZ and sh—SETD2 cells. (B) MTS assays for 786-O cells without or with stably EZH2 knockdown. (C) and (D) Migration and invasion analyses of Transwell for 786-O cells without or with stably EZH2 knockdown. (E) and (F) EdU assays for 786-O cells without or with stably EZH2 knockdown. * P < 0.05 ** P < 0.01 *** P < 0.001.

Journal: PeerJ

Article Title: Genetic alteration of histone lysine methyltransferases and their significance in renal cell carcinoma

doi: 10.7717/peerj.6396

Figure Lengend Snippet: (A) qPCR analysis of relative expression of EZH2 in sh-LacZ and sh—SETD2 cells. (B) MTS assays for 786-O cells without or with stably EZH2 knockdown. (C) and (D) Migration and invasion analyses of Transwell for 786-O cells without or with stably EZH2 knockdown. (E) and (F) EdU assays for 786-O cells without or with stably EZH2 knockdown. * P < 0.05 ** P < 0.01 *** P < 0.001.

Article Snippet: The shRNA plasmids for SETD2 and EZH2 knockdown were constructed from pSicoR (#11579; Addgene, Watertown, MA, USA) with target sequences of shSETD2: TAGTACACCAAGACTCCAG, and shEZH2: CCAACACAAGTCATCCCATTA.

Techniques: Expressing, Stable Transfection, Knockdown, Migration